Fluoxetine, commonly known as Prozac or Reconcile®, is a drug used in dogs and cats with behavioral problems, separation anxiety, and aggression. Sometimes it can also be used as a treatment for itching that does not respond to conventional therapies.
Fluoxetine is an antidepressant that is used to treat depression in people. This drug increases serotonin levels in the brain, a chemical that facilitates the transmission of “messages” between brain cells. Fluoxetine is a prescription drug and can only be used under the supervision of a veterinarian.
Common Name: Reconcile®, Prozac
Type of Drug: SSRIs (Selective Serotonin Reuptake Inhibitors)
Used for: Anxiety Separation, Aggression
Species: Dog, Cat
Administration: Capsules, Tablets, Oral Liquids
Approved by FDA: Yes, for dogs
How Does It Work: Fluoxetine – Prozac
Fluoxetine increases serotonin levels in the central nervous system that is responsible for social interactions, general awareness, and adaptability. To see the first results you have to wait for up to 4 weeks.
Fluoxetine may cause the following side effects:
- – Loss of appetite (most common, usually temporary)
- – Lethargy
- – Vomiting
- – Tremor
- – Diarrhea
Fluoxetine can interact with these drugs:
- – Acepromazine
- – Amitraz
- – Buspirone
- – Cyproheptadine
- – Diazepam
- – Alprazolam
- – Diuretics
- – Insulin
- – Isoniazid
- – MAO Inhibitors (selegiline)
- – Pentazocine
- – Phenytoin
- – Propanolol
- – Metoprolol
- – Tramadol
- – Tricyclic Antidepressants
- – Trazodone
- – Warfarin
Fluoxetine Dosage for Dogs and Cats
Never administer the medication without first consulting the veterinarian.
- For dogs, the dose of fluoxetine is 1/2 mg per kg, administered every 24 hours orally.
- For cats, the dose is 2 to 5 mg once a day.
The duration of administration depends on the condition to treat, the response to the drug, and the development of any side effects. Dogs and cats need to continue treatment for at least 6/8 weeks to get first improvements.
Fluoxetine overdose can cause convulsions. Contact your vet immediately if your dog has taken the overdose of this drug. There may be allergic reactions such as swelling, urticaria, scratches, vomiting, or epilepsy.
The safety of using fluoxetine in pregnant animals has not yet been studied. Do not use in lactating animals, as the medication passes into breast milk.